Mickaël CANOUIL

Curriculum Vitæ

Experience

Jan. 2016 --
Present

Head Biostatistician (CNRS IE2)

Laboratory of Integrated Genomics and Metabolic Diseases Modeling - UMR CNRS 8199, Lille, France

Activities: Genome-wide association studies, experimental design, -omics data analysis, methotological developments, team management

Headed by Pr. P. Froguel
Sept. 2012 --
Dec. 2015

Biostatistician (CNRS IE2)

Laboratory of Integrated Genomics and Metabolic Diseases Modeling - UMR CNRS 8199, Lille, France

Activities: Genome-wide association studies, experimental design, -omics data analysis, methotological developments

Headed by Pr. P. Froguel
Nov. 2011 --
Dec. 2011

Biostatistician

The French Institute of Science and Technology for Transport, Development and Networks (IFSTTAR) - UMRESTTE - UMR T9405, Bron, France

Activities: Analysis of a mobility and accident study in secondary-school pupils

Supervised by Dr. M. Haddak
Jan. 2011 --
Jun. 2011

Biostatistician (Internship)

Hospices Civiles de Lyon - Biostatistics Unit - UMR CNRS 5558, Lyon, France

Activities: Development of a Non-Parametric (on Time) Clustering Algorithm for Longitudinal Data

Supervised by Pr. R. Ecochard et Dr. C. Genolini
Mar. 2010 --
Jun. 2010

Biostatistician (Internship)

Laboratory of Biometry and Evolutionary Biology (LBBE) - UMR CNRS 5558, Lyon, France

Activities: Mathematical Modelling of Nosocomial Rotavirus Infections in Pediatric Ward

Supervised by Dr. C. Kribs-Zaleta

Education

Oct. 2014 --
Present

Doctor of Philosophy (Ph.D.) in BioStatistics

University of Lille 2, Lille, France

Working title: “ Development and Application of Statistical Methods for Longitudinal Genetics Association Studies ”

Supervised by Pr. P. Froguel and Dr. G. Rocheleau
Sept. 2009 --
Jul. 2011

Master's Degree in Biostatistics, Bioinformatics and Genomics

Specialised in Biostatistics

University Claude Bernard Lyon 1, Lyon, France

Sept. 2006 --
Jul. 2009

Bachelor's Degree in Biology

Specialised in Biostatistics

University Claude Bernard Lyon 1, Lyon, France

Computer Skills

Basic
C, SQL
Intermediate
Julia, Lua, Perl, Python, SAS
Advanced
R, LATEX, HTML, css, Markdown

Languages

French
Native
English
Fluent / Full Professional Proficiency
Spanish
Elementary Proficiency

Publications

Variable Clustering in High-Dimensional Linear Regression: The R Package clere

Loïc Yengo, Julien Jacques, Christophe Biernacki and Mickaël Canouil

The R Journal (2016)

Hepatic DPP4 DNA-Methylation Associates With Fatty Liver

Christian Baumeier*, Sophie Saussenthaler*, Anne Kammel, Markus Jähnert, Luisa Schlüter, Deike Hesse, Mickaël Canouil, Stephane Lobbens, Robert Caiazzo, Violeta Raverdy, François Pattou, Emma Nilsson, Jussi Pihlajamäki, Charlotte Ling, Philippe Froguel, Annette Schürmann and Robert W. Schwenk
*These authors contributed equally to the present study.

Diabetes (2016)

Decreased STARD10 Expression is Associated with Defective Insulin Secretion in Humans And Mice

Gaelle R. Carrat, Ming Hu, Marie-Sophie Nguyen-Tu, Pauline Chabosseau, Kyle Gaulton, Martijn van de Bunt, Afshan Siddiq, Mario Falchi, Matthias Thurner, Mickaël Canouil, Francois Pattou, Isabelle Leclerc, Timothy J. Pullen, Matthew C. Cane, Priyanka Prabhala, William Greenwald, Anke Schulte, Piero Marchetti, Mark Ibberson, Patrick MacDonald, Jocelyn E. Manning Fox, Anna L. Gloyn, Philippe Froguel, Michele Solimena, Mark I. McCarthy and Guy A. Rutter

The American Journal of Human Genetics (2017)

Relationship Between Salivary/Pancreatic Amylase and Body Mass Index: A Systems Biology Approach

Amélie Bonnefond*, Loïc Yengo*, Aurélie Dechaume, Mickaël Canouil, Maxime Castelain, Estelle Roger, Frédéric Allegaert, Robert Caiazzo, Violeta Raverdy, Marie Pigeyre, Abdelilah Arredouani, Jean-Michel Borys, Claire Lévy-Marchal, Jacques Weill, Ronan Roussel, Beverley Balkau, Michel Marre, François Pattou, Thierry Brousseau and Philippe Froguel
*These authors contributed equally to the present study. These authors contributed equally to the present study.

BMC Medicine (2017)

Communications

Oral Presentations

Julia for Intensive Scientific Computing

Mickaël Canouil

National Days of Higher Education and Research Software Developpement - JDEV, Bordeaux, France (2015)

Longitudinal Genetic Modelling: Revisiting Associations of SNPs Associated with Blood Fasting Glucose in Normoglycemic Individuals

Mickaël Canouil, Ghislain Rocheleau, Loïc Yengo and Philippe Froguel

Statistical Methods for Post Genomic Data - SMPGD, Lille, France (2016)

Poster Presentations

Application of Joint Models in Genetic Association Studies

Ghislain Rocheleau, Mickaël Canouil, Loïc Yengo and Philippe Froguel

International Genetic Epidemiology Society - IGES, Baltimore, United-States (2015)

Single Nucleotide Polymorphisms Associated with Fasting Blood Glucose Trajectory and Type 2 Diabetes Incidence: A Joint Modelling Approach

Mickaël Canouil, Philippe Froguel and Ghislain Rocheleau

International Genetic Epidemiology Society - IGES, Toronto, Canada (2016)

Awards

2015

Funding Allocation SFD-Lilly

French speaking Diabetes Society (SFD), Bordeaux, France

“ Detection of New Genomic Variants Associated with Fasting Blood Glucose and Incidence of Type 2 Diabetes Simultaneously ”

http://www.sfdiabete.org

R Packages

snpEnrichment

R package implementing a method for calculating an enrichment statistic of a set of SNP within a GWA signal

Mickaël Canouil and Loïc Yengo (2013)

https://cran.r-project.org/package=snpEnrichment

clere

R package implementing the CLERE methodology

Loïc Yengo, Julien Jacques, Christophe Biernacki and Mickaël Canouil (2014)

https://cran.r-project.org/package=clere